Sources: 
Y Combinator’s spring 2025 accelerator batch has spotlighted agentic AI startups, investing $500,000 in each of the 70 selected companies. Among them, Plexe, founded by Vaibhav Dubey and Marcello De Bernardi in San Francisco, is pioneering open-source AI agents that generate predictive machine-learning models from natural language prompts.
This approach aims to democratize machine learning by enabling users to build models without extensive coding expertise. Plexe’s technology leverages natural language inputs to create sophisticated predictive tools, potentially reshaping how AI models are developed and deployed.
The intensive three-month program supports startups like Plexe alongside others such as Galen AI, which integrates healthcare and fitness data for personalized advice, and Approval AI, which automates mortgage processes.
“Plexe builds open-source agents that build predictive machine-learning models from natural language prompts,” highlighting its innovative edge in the AI landscape.
Y Combinator’s commitment to agentic AI reflects a broader trend toward autonomous, intelligent systems capable of complex decision-making and automation.
“Y Combinator's spring 2025 batch featured 70 startups focused on agentic AI,” underscoring the accelerator’s strategic focus on this emerging technology sector.
With substantial funding and mentorship, Plexe and its cohort are positioned to influence the future of AI development, emphasizing accessibility and open-source collaboration.
This investment signals growing confidence in AI agents that can interpret natural language to build predictive models, potentially transforming industries reliant on machine learning.
Sources: Y Combinator’s spring 2025 batch invested $500,000 in Plexe, a startup building open-source AI agents that create predictive machine-learning models from natural language prompts. Plexe, founded by Vaibhav Dubey and Marcello De Bernardi, is part of a 70-startup cohort focused on agentic AI innovations.