Machine learning model enhances human-centered drug toxicity prediction; Dr. Min-hyuk Park says it will be a practical tool in new drug development

A new machine learning model has been developed to predict drug toxicity, aiming to improve safety in drug development. Dr. Min-hyuk Park emphasizes that this model will serve as a practical tool to identify high-risk drugs early in clinical trials.

Sources:
News-Medical
Trending 2h ago
Tab background
Sources: News-Medical
A machine learning model developed by Dr. Min-hyuk Park significantly enhances the prediction of drug toxicity, an innovation that could transform drug development.
Validation of the model involved data from 434 hazardous and 790 approved drugs, establishing strong links between genetic characteristics and toxicity-related drug failures.
The model's predictive accuracy surpasses existing technologies, marking it as a pioneering advancement in understanding genotype-phenotype relationships relevant to drug safety.
Park emphasized, 'The human-centered toxicity prediction model will be a very practical tool in new drug development.' This cutting-edge approach promises to evolve as more data is incorporated, leading to increased effectiveness in preclinical evaluations.
The implications of this model could drastically reduce risks associated with drug trials and expedite the introduction of safer pharmaceuticals to the market.
Sources: News-Medical
A new machine learning model developed by Dr. Min-hyuk Park aims to enhance drug toxicity predictions, identifying dangerous drugs before clinical trials. The model outperformed existing systems and is anticipated to significantly facilitate the drug development process, according to Park and collaborator Woomin Song.
Section 1 background
Key Facts
  • Machine learning advances in drug toxicity prediction could enhance safety in clinical trials.News-Medical
  • Validation using data from 434 hazardous drugs and 790 approved drugs revealed significant associations with drug failure due to toxicity.News-Medical
  • The developed AI model shows superior predictive performance compared to existing state-of-the-art models.News-Medical
  • This represents the first attempt to include differences in genotype-phenotype relationships in toxicity predictions.News-Medical
  • Dr. Min-hyuk Park stated that the human-centered toxicity prediction model will be a very practical tool in new drug development.News-Medical
  • The framework aims for early identification of high-risk drugs during clinical development.
  • The model's effectiveness is projected to improve as more data becomes available.News-Medical
A machine-learning-based technology has been developed to learn these differences and preemptively identify potentially dangerous drugs before clinical trials.
News-Medical
News-Medical
Article not found
CuriousCats.ai

Article

Source Citations