- NASA has joined the Genesis Mission, a White House-led initiative aimed at expanding the use of artificial intelligence to tackle scientific and engineering challenges.
- The U.S. Department of Energy has invested in Fermilab projects to accelerate AI-enabled scientific discovery, which includes funding for an AI/ML project led by Fermilab.
- Fermilab is recognized as a strong contributor to the Genesis Mission, demonstrating its leadership in applying artificial intelligence and advanced technologies to accelerate scientific discovery.
- The Genesis Mission is a historic national initiative led by the U.S. Department of Energy, aimed at building the world’s most powerful integrated science discovery platform.
- NASA is assessing how its missions, data holdings, and technical expertise could support the initiative’s National Science and Technology challenges, including developing AI tools aligned with the mission’s objectives.
- Fermilab will lead a project to develop AI/ML-based resonance control algorithms to improve the performance of particle accelerators that drive discovery science.
NASA has joined the Genesis Mission, a historic initiative led by the U.S. Department of Energy (DOE) to leverage artificial intelligence (AI) for scientific advancements. The mission aims to enhance the use of AI across various federal agencies, focusing on energy, discovery science, and national security.12345
Fermilab has been awarded funding for an AI/ML project that will develop resonance control algorithms to improve particle accelerator operations. This project is part of a broader portfolio that includes collaborations with national labs, universities, and industry partners like xLight Inc. Fermilab Director Norbert Holtkamp expressed gratitude for the support, stating, “This investment strengthens our ability to accelerate scientific discovery, develop next-generation technologies, and drive innovation at the frontiers of particle physics and advanced technology.”6
The Genesis Mission, initiated by an executive order from President Donald J. Trump, aims to create the world’s most powerful integrated science discovery platform. NASA Administrator Jared Isaacman highlighted the mission's potential, saying, “The Genesis Mission is an opportunity to turn that foundation into faster science, stronger engineering, and better mission outcomes.” NASA plans to utilize its extensive data holdings, which include over 150 petabytes of information, to derive new insights and improve predictions through AI tools.

As the Genesis Mission progresses, NASA will explore how AI can enhance its capabilities in various domains, including spacecraft operations and data analysis, ultimately aiming to maintain U.S. leadership in space and foster innovation in scientific research.
“Fermilab's project will develop AI/ML resonance control algorithms to improve accelerator operations. Two Cornell-led projects received nearly $1.2 million to create AI models for complex turbulent flows and predict electronic properties of materials.”
